Results 141 to 150 of about 2,365,288 (278)

Fuzzy Logic and Intelligent Agents: Towards the Next Step of Capital Budgeting Decision Support [PDF]

open access: yes
The economic life of large investments is long and thus necessitates constant dynamic managerial actions. To be able to act in an optimal way in the dynamic management of large investments managers need the support of advanced analytical tools. They need
Collan, Mikael, Liu, Shuhua
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The Decision Support System Design Of Employee Performance Appraisal Using Analytical Hierarchi Process (AHP) Method

open access: yes, 2012
A performance appraisal is important for every employee and it is also useful for companies to assign the next policy action. In RS Roemani, the performance appraisal process is used for the promotion, the performance evaluation, the hajj subsidy, the ...
Rochmat , Taufiq
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Information-analytical complex of support of transdisciplinary researches processes

open access: yesEnvironmental safety and natural resources, 2018
V.V. Prychodniuk   +3 more
openaire   +2 more sources

Enhancement of Procedure of Budget Process Informational-Analytic Support Совершенствование процедуры информационно-аналитической поддержки бюджетного процесса

open access: yesBìznes Inform, 2012
The article is devoted to analysis of regional peculiarities and development of information file forming procedure and model parametrization in the budget process support project.Статья посвящена анализу региональных особенностей и усовершенствованию процедуры формирования информационного массива и параметризации моделей в рамках проекта поддержки ...
Polyakova Olga Yu.   +2 more
openaire   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Aeroelastic effects in multirotor vehicles. Part 2: Methods of solution and results illustrating coupled rotor/body aeromechanical stability [PDF]

open access: yes
This report is a sequel to the earlier report titled, Aeroelastic Effects in Multi-Rotor Vehicles with Application to Hybrid Heavy Lift System, Part 1: Formulation of Equations of Motion (NASA CR-3822).
Friedmann, P. P., Venkatesan, C.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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