Results 161 to 170 of about 1,459,315 (301)

Beyond STRs: Integrative Forensic Genomics from MPS to Genetic Genealogy and AI-Based Prediction. [PDF]

open access: yesGenes (Basel)
Brancato D   +7 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

THE USING OF THE ELECTRONIC SYSTEMS OF OPEN ACCESS FOR INFORMATION AND ANALYTICAL SUPPORT PEDAGOGICAL RESEARCH

open access: yes, 2016
The article deals with the feasibility of the using of the electronic systems of open access for information and analytical support of scientific research, including: publications of the domestic and foreign scholars which dedicated the using of the ...
Liliia A. Luparenko   +4 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Other title: IT Service Catalog; Other title: Information Technology Service Catalog; Other title: Service Catalog

open access: yes, 2010
application/pdf; "July 2010.""The Division of Information Systems and Communications, also known as DISC, is a fee-based organization comprised of seven operational units that deliver 24 x 7 central information technology services such as statewide data,
Kansas. Department of Administration. Division of Information Systems and Communications.
core  

Development of K-CORE: a web-based platform for integrated clinico-genomic analysis. [PDF]

open access: yesLife Sci Alliance
Hwang J   +14 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Digital tools for information and Analytical Support for the Training of Research and Teaching Staff [PDF]

open access: yes
На реалізацію другого, аналітико-синтетичного, етапу наукового дослідження «Інформаційно-аналітичний супровід цифрової трансформації освіти: вітчизняний і зарубіжний досвід» у 2024 році представлено результати розроблення проблеми за підтемою «Теоретико ...
Ростока, Марина Львівна
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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