Results 81 to 90 of about 22,983,555 (247)

Information and analytical support of public procurement in Ukraine

open access: yes, 2019
The subject of the study is the peculiarities of informational and analytical provision of processes for the formation and implementation of public procurement.
RUDCHENKO A.Y., BESPALOVA А.V
core   +1 more source

Development of the Strategic Monitoring Concept for Ukraine's National Security and Resilience Based on the Practical Implementation of the SOTA Information and Analytical System

open access: yesMilitary science
This article examines the development of the Strategic Monitoring Concept for Ukraine's National Security and Resilience based on a synthesis of the practical implementation outcomes of the SOTA networked information and analytical system.
Микола Добиш   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A Decision Support Model for the Selection of Best Value Information Technology Procurement Method [PDF]

open access: yes, 2008
SUMMARY: The procurement of Information Technology (IT) is as important as the use of the technology. Procurement includes two aspects: the selection of the right IT product as well as the selection of the method to procure it.
Perera, Srinath (R18622)   +2 more
core  

Preferance of computer technology for analytical support of large database of medical information systems [PDF]

open access: yesСаратовский научно-медицинский журнал, 2013
Aim: to study the use of intelligent technologies for analytical support of large databases of medical information systems. Material and methods. We used the techniques of object-oriented software design and database design. Results.
Biryukov А.P.   +5 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An analytical inspection framework for evaluating the search tactics and user profiles supported by information seeking interfaces

open access: yes, 2009
Searching is something we do everyday both in digital and physical environments. Whether we are searching for books in a library or information on the web, search is becoming increasingly important.
Wilson, Max L.   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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