Results 91 to 100 of about 17,793,564 (291)

Consumer-Centric Protection for Online Social Networks [PDF]

open access: yes, 2014
Online Social Networks (OSNs) are a unique construct that is shaped by the advancement and availability of Internet technologies. A large portion of internet users make use of OSN services to share and celebrate their personal lives with friends and ...
Tsz Fung Law   +7 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Network Tomography for Information-Centric Networking

open access: yesIEICE Transactions on Communications, 2022
KAWAHARA, Ryoichi   +3 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Information-Centric Networking (ICN) Adaptation to Low-Power Wireless Personal Area Networks (LoWPANs)

open access: yes, 2021
This document defines a convergence layer for Content-Centric Networking (CCNx) and Named Data Networking (NDN) over IEEE 802.15.4 Low-Power Wireless Personal Area Networks (LoWPANs).
Wählisch, Matthias   +5 more
core   +1 more source

Interest Forwarding in Named Data Networking Using Reinforcement Learning

open access: yesSensors, 2018
In-network caching is one of the key features of information-centric networks (ICN), where forwarding entities in a network are equipped with memory with which they can temporarily store contents and satisfy en route requests.
Olumide Akinwande
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy