Results 101 to 110 of about 8,070,640 (223)

Advising on Antidepressant Use in Pregnancy: Are We All on the Same Page? [PDF]

Asia Pac Psychiatry
Broughton LC, Hughes N, Zeng J, Smith A.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Newborns' Language Discrimination May Not Reflect Sensitivity to Speech Rhythm: Evidence From Computational Modeling. [PDF]

Dev Sci
Famularo RL, Aboelata A, Schatz T, Feldman NH.   +3 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Author Guideline

Jurnal Teknik Industri, 2016
Editorial Information
doaj   +1 more source

Realist process evaluation of a co-designed intervention to address the unmet information needs of people with dementia and their family carers. [PDF]

PLoS One
De Poli C.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Response to LTE "Bridging the Gap Between Patient Experience and System-Level Review: A Call for Discipline-Specific Communication in Hospital-to-Home Transitions. [PDF]

Health Expect
van Grootel J, Collet R, Major M, Wiertsema S, van Dongen J, van der Leeden M, Geleijn E, Ostelo R, van der Schaaf M.   +8 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Tetanus Health Information on YouTube and TikTok: Cross-Sectional Analysis of Quality, Reliability, and Public Health Implications. [PDF]

JMIR Infodemiology
Huang R, Shen Y, Zou G, Zhou J, Deng X, Li Q, Chen X.   +6 more
europepmc   +1 more source