Results 181 to 190 of about 5,045,493 (316)

Information Access and Use by Patients With Cancer and Their Friends and Family: Development of a Grounded Theory. [PDF]

J Med Internet Res, 2020
Thiessen M, Sinclair S, Tang PA, Raffin Bouchal S.   +3 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Listening to Australians with ovarian cancer: a cross-sectional survey investigating clinical trials awareness, information access and participation. [PDF]

Support Care Cancer
Williams N, Lee YC, Russell H, Andrews J, Chen WS, Bradhurst B.   +5 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Tracking down on 50-year History of Research about Information Management and Technology in Korea [PDF]

, 2013
Dept. of Domestic Information Information Service Center Korea Institute of Science and Technology Information, Dept. of Domestic Information, Information Service Center, Korea Institute of Science and Technology Information   +1 more
core   +1 more source

Exploring Information Access in Aging Populations and Those With Dementia and Mild Cognitive Impairment in the United Kingdom: Survey and Focus Group Study. [PDF]

JMIR Aging
Rogers C, McGeown WJ, Moshfeghi Y.
europepmc   +1 more source

Parental Online Information Access and Childhood Vaccination Decisions in North America: Scoping Review. [PDF]

J Med Internet Res, 2020
Ashfield S, Donelle L.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cervical cancer information access and dissemination strategies among rural Kenyan women: A mixed methods study. [PDF]

J Public Health Afr
Chepkorir J, Kivuti-Bitok L, Perrin N, Gross D, Gallo JJ, Anderson J, Reynolds NR, Wyche S, Kibet H, Kipkuri V, Cherotich A, Guillaume D, Han HR.   +12 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source