Results 31 to 40 of about 2,002,674 (275)

Autonomic Properties in Traffic Control

Cybernetics and Information Technologies, 2013
The operation of a complex system like a transportation network is considered with respect to the opportunities to identify the application of autonomic properties. The autonomic features of self-properties are analyzed.
Stoilova Krasimira, Stoilov Todor, Nikolov Konstantin   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Adaptation for a Changing Environment: Developing learning and teaching with information and communication technologies [PDF]

, 2006
This article examines the relationship between the use of information and communication technologies (ICT) and learning and teaching, particularly in distance education contexts.
Kirkwood, Adrian, Price, Linda
core   +4 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A review of the use of information and communication technologies for dietary assessment [PDF]

, 2009
Presently used dietary-assessment methods often present difficulties for researchers and respondents, and misreporting errors are common. Methods using information and communication technologies (ICT) may improve quality and accuracy.
Engelen, Anouk, García-Segovia, Purificación, Molag, Marja, Ngo, Joy, Roesle, Joni, Serra-Majem, Lluís   +5 more
core   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

INNOVATIVE METHODS OF EVALUATING THE EFFICIENCY OF ADVERTISING ACTIVITIES WITHIN THE FRAMEWORK OF DIGITAL STRATEGY (ON THE EXAMPLE OF «NOVA POST LLC»)

Економіка та суспільство
The article provides a comprehensive analysis of the evolution of methods for evaluating advertising effectiveness in the context of digital transformation and the growing role of data-driven decision-making. The limitations of traditional metrics (ROI,
Ольга Ромащенко, Павлов Павлов, Анастасія Свиридюк   +2 more
doaj   +1 more source

3D Visualization of Sound Fields Perceived by an Acoustic Camera

Cybernetics and Information Technologies, 2015
The paper summarizes the application results of a recently proposed neuro-fuzzy algorithm for multi-dimensional data clustering to 3-Dimensional (3D) visualization of dynamically perceived sound waves recorded by an acoustic camera. The main focus in the
Popova Nevena, Shishkov Georgi, Koprinkova-Hristova Petia, Alexiev Kiril   +3 more
doaj   +1 more source