Results 41 to 50 of about 445,436 (311)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

INNOVATIVE METHODS OF EVALUATING THE EFFICIENCY OF ADVERTISING ACTIVITIES WITHIN THE FRAMEWORK OF DIGITAL STRATEGY (ON THE EXAMPLE OF «NOVA POST LLC»)

open access: yesЕкономіка та суспільство
The article provides a comprehensive analysis of the evolution of methods for evaluating advertising effectiveness in the context of digital transformation and the growing role of data-driven decision-making. The limitations of traditional metrics (ROI,
Ольга Ромащенко   +2 more
doaj   +1 more source

3D Visualization of Sound Fields Perceived by an Acoustic Camera

open access: yesCybernetics and Information Technologies, 2015
The paper summarizes the application results of a recently proposed neuro-fuzzy algorithm for multi-dimensional data clustering to 3-Dimensional (3D) visualization of dynamically perceived sound waves recorded by an acoustic camera. The main focus in the
Popova Nevena   +3 more
doaj   +1 more source

Reduced Multiplicative (BURA-MR) and Additive (BURA-AR) Best Uniform Rational Approximation Methods and Algorithms for Fractional Elliptic Equations

open access: yesFractal and Fractional, 2021
Numerical methods for spectral space-fractional elliptic equations are studied. The boundary value problem is defined in a bounded domain of general geometry, Ω⊂Rd, d∈{1,2,3}. Assuming that the finite difference method (FDM) or the finite element method (
Stanislav Harizanov   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Information and Communications Technology in Education [PDF]

open access: yes, 2015
As Information and Communication Technologies (ICT) gradually permeate daily life, they are profoundly changing the way education is conceived and delivered. Teachers play a key role in this transformation process; their beliefs, pedagogical practices, and teaching skills are continuously challenged.
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

LightIN: a versatile silicon-integrated photonic field programmable gate array with an intelligent configuration framework for next-generation AI clusters

open access: yesLight: Science & Applications
Artificial Intelligence models pose serious challenges to intensive computing and high-bandwidth communication for conventional electronic circuit-based computing clusters.
Ying Zhu   +16 more
doaj   +1 more source

Performance evaluation of Cuckoo filters as an enhancement tool for password cracking

open access: yesCybersecurity, 2023
Cyberthreats continue their expansion, becoming more and more complex and varied. However, credentials and passwords are still a critical point in security.
Maria-Dolores Cano   +2 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

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