Results 41 to 50 of about 2,002,674 (275)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Performance evaluation of Cuckoo filters as an enhancement tool for password cracking

open access: yesCybersecurity, 2023
Cyberthreats continue their expansion, becoming more and more complex and varied. However, credentials and passwords are still a critical point in security.
Maria-Dolores Cano   +2 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The mathematical method for assessing the cybersecurity state of cloud services

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
This study presents the developed mathematical method for assessing the cybersecurity state of cloud services of information infrastructure facilities.
Yevheniia Ivanchenko   +4 more
doaj   +1 more source

Information and Communication Technologies and Informal Scholarly Communication: A Review of the Social Oriented Research [PDF]

open access: yes, 2009
This article reviews and analyzes findings from research on computer mediated informal scholarly communication. Ten empirical research papers, which show the effects and influences of information & communication technologies (ICTs), or the effects of ...
Lin, Chi-Shiou, Yuan, Da-Yu
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Towards Robust Evaluation of Aesthetic and Photographic Quality Metrics: Insights from a Comprehensive Dataset

open access: yesComplexity
In recent years, the development of metrics to evaluate image aesthetics and photographic quality has proliferated. However, validating these metrics presents challenges due to the inherently subjective nature of aesthetics and photographic quality ...
Iria Santos   +5 more
doaj   +1 more source

Beam-steering metasurfaces assisted coherent optical wireless multichannel communication system

open access: yesNanophotonics, 2023
The metasurface based beam-steering devices with the advantages of large steering angles, arbitrary channels and ultra-compactness have played an important role for data allocation and exchange in the optical wireless communication.
Tao Jin   +13 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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