Results 71 to 80 of about 15,902,992 (272)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

‘I’d rather not have known this’: a study of information regret

Information Research: An International Electronic Journal
Introduction. This article introduces the concept of ‘information regret’, which refers to the phenomenon where people regret having received certain information, challenging the typical information science view that obtaining information is always ...
Dirk Lewandowski
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Rethinking information practices to embrace avoidance: everything old is new again

Information Research: An International Electronic Journal
Introduction. We respond to Hicks et al.’s (2025) call to reconceptualise information avoidance free from the assumption that avoiding information is necessarily negative, denialist, or non-compliant.
Jenny Bronstein, Alison Hicks, Jette Seiden Hyldegård, Pam McKenzie, Ian Ruthven   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

UAV collision avoidance: a specific acceleration matching approach [PDF]

, 2011
Includes abstract.Includes bibliographical references.An increased level of autonomy is required for future Unmanned Aerial Vehicle (UAV) missions. One of the technologies required for this to occur is an adequate sense and avoid system to enable the UAV
Patel, Amir
core   +1 more source

Singing in the rain: the role of umbrella concepts in library and information science

Information Research: An International Electronic Journal
Introduction. This paper considers the function and use of umbrella concepts within the library and information science (LIS) discipline. Method.
Ian Ruthven, Alison Hicks, Pamela J. McKenzie, Jenny Bronstein, Jette Seiden Hyldegård, Gunilla Widén   +5 more
doaj   +1 more source

An exploratory study of information avoidance behavior of undergraduate students in monitoring their academic goal progress

, 2021
Background. Much of the literature on information behavior explores information seeking. Active acquisition of information is attributed to knowledge and certainty, whereas avoidance is perceived as counter to the norm of information seeking. However,
Baxa, Patricia Marie L., Apolinario, Rhea Rowena U.   +1 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A reinforcement learning framework for information-seeking and information-avoidance.

, 2023
info:eu-repo/semantics ...
Cogliati Dezza, Irene, Molinaro, Gaia, Verguts, Tom   +2 more
openaire   +2 more sources