Results 171 to 180 of about 1,859,644 (362)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
ANSI/NISO Z39.50 : Information retrieval : Application service definition & protocol specification
, 2003 "An American National Standard Developed by the National Information Standards Organization"La Library of Congress actualiza esta norma.Revisado en 2014.Esta norma define un servicio basado en un cliente/servidor y un protocolo para la recuperación de ...
American National Standards Institute +1 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
THE ROLE OF AGRICULTURE IN OREGON'S ECONOMIC BASE: FINDINGS FROM A SOCIAL ACCOUNTING MATRIX
Most studies of a state’'s economic base count as “"basic”" only the “"traditional"” exports of goods, federal spending, and business investment. “"Nontraditional”" elements of the economic base (including exports of services, federal transfers to
Holland, David W. +2 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Base-rate Respect by Intuition: Approximating Rational Choices in Base-rate Tasks with Multiple Cues [PDF]
Although intuitive-automatic processes sometimes lead to systematic biases in judgment and choice, in many situations especially this kind of processes enables people to approximate rational choices.
Stephan Dickert, Andreas Glöckner
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
User participation and user satisfaction in information systems development
, 2001 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 26/06/2001.Information Systems (IS) are being developed and used in organizations to achieve their business goals and to enhance organizational ...
Bokhari, Rahat Hussain, Bokhari, R.H.
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source