Results 91 to 100 of about 7,016,790 (301)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Utilization of Historic Information in an Optimisation Task [PDF]
, 1984 One of the basic components of a discrete model of motor behavior and decision making, which describes tracking and supervisory control in unitary terms, is assumed to be a filtering mechanism which is tied to the representational principles of human ...
Boesser, T.
core +1 more source
Disease information-seeking behavior [PDF]
Science, 2016 Infectious Disease![Figure][1] Google Trends data allow for monitoring of disease outbreaks. PHOTO: HARTPHOTOGRAPHY/[SHUTTERSTOCK.COM][2] Chicken pox is usually a mild disease of children and, consequently, national vaccination and reporting policies vary widely. In countries that do not immunize against chicken pox, Google Trends recorded a strong
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Information Behavior in the Mobile Environment: An Overview [PDF]
, 2016 As smartphones become ubiquitous, they increasingly influence the way in which students seek and use information. It is important to understand emerging information behavior as a result of wide spread use of smartphones.
Liu, Ziming
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Effective attributed network embedding with information behavior extraction. [PDF]
PeerJ Comput Sci, 2022 Hu G, Pang J, Mo X.
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Comercio electrónico del flamenco: textiles, zapatos y complementos. Electronic-commerce of flamenco: textiles, shoes and accessories [PDF]
Revista del Centro de Investigación Flamenco Telethusa, 2013 El flamenco forma parte del patrimonio inmaterial de la humanidad y también es considerado un sector económico de gran potencial, formando parte de las industrias culturales de España.
Antonia Hurtado Guapo +2 more
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