Results 111 to 120 of about 2,161,269 (246)

Estructura del Sistema de Gestión Integral de Documentos de archivo [SiGeID 1.0]

open access: yesRevista Interamericana de Bibliotecología, 2012
The new context imposes on organizations the vital necessity of having appropriate communication infrastructures that allow them to get actual and enough knowledge about their environment.
Dominica Legañoa Ferrá   +5 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

The Information Behavior of Indonesian Faculty Members on Social Media

open access: yesJournal of Information Science Theory and Practice, 2019
Currently there are many groups of Indonesian faculty members on social media. This research aims to find out the information behavior of Indonesian faculty members on social media, especially on Facebook, Telegram, and WhatsApp.
Kurniasih, Nuning
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A Comparative Analysis of Collaborative Information Behavior Models in Information Behavior Research

open access: yesJournal of the Korean Society for information Management, 2013
협동적 정보행태에 대한 연구의 중요성이 대두됨에 따라, 다양한 문제 상황에서 협동적 정보행태에 대한 많은 수의 연구가 수행되어 왔고, 그를 바탕으로 여러 모형이 제안되고 있다. 본 연구에서는 Prekop(2002), Reddy와 Jansen(2008), Shah(2008), Karunakaran, Spence와 Reddy(2010), Yue와 He(2010) 등이 제안한 5개의 협동적 정보행태 모형들을 비교 분석하고, 그 결과를 토대로 향후 협동적 정보행태 연구의 지향점을 논의하였다. 협동적 정보행태에 대한 기존 연구의 한계를 극복하고 후속 연구를 위한 전략은 다음과 같다.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A process-based approach to exploring the information behavior of informal caregivers of people living with dementia. [PDF]

open access: yesInt J Med Inform, 2021
Rutkowski RA   +5 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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