Results 171 to 180 of about 18,276,657 (278)

A framework for understanding culture and its relationship to information behaviour: Taiwanese aborigines' information behaviour.

open access: yesInf. Res., 2007
Introduction. This article proposes a model of culture and its relationship to information behaviour based on two empirical studies of Taiwanese aborigines' information behaviour. Method. The research approach is ethnographic and the material was collected through observations, conversations, questionnaires, interviews and relevant documents.
openaire   +2 more sources

The Role of Information Deserts in Information Security Awareness and Behaviour

open access: yesProceedings of the 8th International Conference on Information Systems Security and Privacy, 2022
Dirk P. Snyman, Hennie A. Kruger
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Managing collaborative information sharing : Bridging research on information culture and collaborative information behaviour

open access: yes, 2012
Introduction. The aim of this paper is to combine insights of collaborative information behaviour and information cultures in organizations to bridge different aspects of managing knowledge-creation and information sharing in order to highlight the ...
Hansen, Preben,, Widén, Gunilla,
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Information Outdoors: Exploring the Information Behaviour of Hobby Campers [PDF]

open access: yes
This thesis is an exploratory, ethnographic study of the information behaviour of participants in the camping hobby. Employing a demographic questionnaire, semi-structured interviews, and participant observation with fieldnotes of ten hobby campers who ...
Lamont, Laura Emily
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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