Results 171 to 180 of about 689,793 (290)
Transdisciplinarity: an imperative for information behaviour research
Information Research: An International Electronic JournalIntroduction. Information behaviour research must be methodologically and conceptually sophisticated to generate knowledge reflecting the complexities of information engagement in people’s lives.
Sarah Polkinghorne +2 more
doaj
Online health information behaviour and its association with statin adherence in patients with high cardiovascular risk: A prospective cohort study. [PDF]
Digit HealthLim HM +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Representational exchange and edgework: towards theorising the coping with fragmentary information
Information Research: An International Electronic JournalIntroduction. People face often situations when the available information is fragmentary and epistemically and ontologically different stemming from multiple incongruous systems of knowledge.
Isto Huvila
doaj
Contrary to the conventional view that strong leader-member relationships naturally guarantee proactive cybersecurity efforts, this study uncovers a more intricate reality: caring leadership without tangible employee empowerment and accountability can ...
Furnell, Steve +3 more
core
Digested Information as an Information Theoretic Motivation for Social Interaction [PDF]
Within a universal agent-world interaction framework, based on Information Theory and Causal Bayesian Networks, we demonstrate how every agent that needs to acquire relevant information in regard to its strategy selection will automatically inject part ...
Christoph Salge, Daniel Polani
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Partnership: The Canadian Journal of Library and Information Practice and Research, 2012 Margaret Sampson
doaj +1 more source