Results 241 to 250 of about 18,276,657 (278)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Nurse-Led Instant Message-Delivered Dyadic Intervention in Sodium Intake Reduction Knowledge, Attitude and Practice in Hypertensive Stroke Survivors: Randomised Controlled Trial Protocol. [PDF]

Nurs Open
Yan Y, Wang MP, Lau KK, Chen H, Yang Y, Yang Z, Ye F, Lee JJ.   +7 more
europepmc   +1 more source

Author Correction: On the conversational persuasiveness of GPT-4. [PDF]

Nat Hum Behav
Salvi F, Horta Ribeiro M, Gallotti R, West R.   +3 more
europepmc   +1 more source

Determinant factors of sexual and reproductive health literacy among adolescents in Indonesia: A national population-based study. [PDF]

J Educ Health Promot
Darmawan WS, Saputro SA, Sono S, Suryadarma AY, Destiwi M, Bassey PE.   +5 more
europepmc   +1 more source