Results 101 to 110 of about 599,039 (303)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Being in place: embodied information practices

, 2017
Introduction. The concept of embodied information practices and the implications for research and professional practice are examined drawing from the authors’ empirical studies of people engaged in professional and everyday practices. The authors suggest
Olsson, MR
core  

Models and theories that can guide grief and bereavement information interventions: an information behaviour lens

Information Research: An International Electronic Journal
Introduction. Information behaviour in grief, bereavement, death, dying and its influence on the development of information interventions is understudied.
Ina Fourie
doaj   +3 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Bibliometric analysis of information seeking behaviour related literature

, 2004
The paper deals with a study conducted on literature related to information seeking behaviour from LISA Plus. The out come of the normal keyword search in LISA Plus are analysed to present the growth of publications; collaboration-ship pattern of authors;
Parmar, Arvind Singh, Prakash, Thushara, Kumar, Sanghmitra A.   +2 more
core  

Epistemology and Information Seeking Behaviour: Outcome of a Quantitative Research

Iranian Journal of Information Processing & Management, 2009
The present study intended to study the state of information seeking among 158 graduate students in University of Tehran and examine its correlation with students’ epistemological beliefs.
Mahmood Khowsrojerdi
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Navigating subjectivity in causal context: a non-deterministic approach for information behaviour research

Information Research: An International Electronic Journal
Introduction. Information behaviour research often asks causal questions with tools that describe associations. Conventional, regression-based models struggle when constructs are subjective, context-bound, and difficult to estimate. The academic setting
Marek Deja
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source