Results 151 to 160 of about 599,039 (303)
Information-seeking behaviour of Slovenian researchers: implications for information services
, 2011 The paper present one part of a survey of information behaviour of Slovenian researchers. Results show that Slovenian researchers in most areas show usual traits of scholarly information behaviour. Exceptions are the non-use of Web 2.0 tools for research purposes and low use of open-access materials.
Vilar, Polona (UNI-LJ) +3 more
openaire
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The concept of usefulness in library and information science research [Elektronisk resurs]
, 2019 There is not much doubt that information, information services and systems need to be useful. In this light, the relatively lack of conceptual elaboration of the concept of usefulness in the library and information science literature can be regarded as ...
Hirvonen, Noora, +3 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Information behaviour of music record collectors
, 2014 Introduction: Using Stebbins's concept of 'serious leisure' and Savolainen's concept of 'everyday life information practices', this study explores the information behaviour of music record collectors. Method: An ethnographic approach was used for the
Price, L. +3 more
core
Introduction. The aim of this paper is to explore the investigation of information-seeking behaviour in the literature of psychology, with special reference to the period before 1981, when the term was introduced into information science, and compare ...
Wilson, Tom,
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Inf. Res., 2019 Introduction. This paper focuses on a research strategy combining the concept of mental models, diary method, drawings technique and thematic analysis to study individual information spaces. The possibility of implementing such approach was tested on a case study of personal information spaces of undergraduate information management students.
Cisek, Sabina, Krakowska, Monika
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source