Results 131 to 140 of about 599,039 (303)

Bringing human information behaviour into information systems research: an application of systems modelling

open access: yesInformation Research: An International Electronic Journal, 2004
In their influential paper, Dervin and Nilan compared and contrasted the "traditional" and "alternative" paradigms for human information behaviour research, highlighting the inadequacies of the former and promoting the importance of ...
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A hermeneutic investigation of online consumer decision making

open access: yes, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 16/06/2005.This is a multidisciplinary information systems thesis with a strong sociological focus.
Cole, Melissa
core  

An investigation of information seeking behaviour of Computer Science and Information Technology undergraduates: a qualitative approach [PDF]

open access: yes, 2009
It is a common fallacy to assume that undergraduates are skilled in finding and evaluating resources for their various learning needs. Information professionals need to find out strategies and courses of action undertaken by undergraduate students in ...
Zainab, A.N.   +3 more
core  

A framework for understanding culture and its relationship to information behaviour: Taiwanese aborigines' information behaviour

open access: yesInformation Research: An International Electronic Journal, 2007
Introduction. This article proposes a model of culture and its relationship to information behaviour based on two empirical studies of Taiwanese aborigines' information behaviour. Method.
Nei-Ching Yeh
doaj  

The Impact of Socio-Demographic Characteristics on Amulet Collectors’ Information-Seeking Behaviours

open access: yesJournal of Information Science Theory and Practice
Thailand’s amulet business is a Buddhist commercial sector with substantial economic importance. As a result, many individuals interested in purchasing religious items seek information to guide their buying decisions.
Jaturong Chitiyaphol   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Researchers of tomorrow: the research behaviour of Generation Y doctoral students [PDF]

open access: yes, 2012
Researchers of Tomorrow is the UK’s largest study to date on the research behaviour of Generation Y doctoral students (born between 1982 and 1994). JISC and the British Library jointly commissioned the three year study in 2009, which involved 17,000 ...

core  

Information behaviour that keeps found things found

open access: yesInformation Research: An International Electronic Journal, 2004
This paper reports on a study that the researchers call: 'Keeping found things found on the Web' or 'KFTF'. The research focuses on the classic problem of ensuring that once a useful information source or channel has been located, it can be found again ...
Harry Bruce, William Jones, Susan Dumais
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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