Results 61 to 70 of about 15,576,316 (273)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Distributed clustering of categorical data using the information bottleneck framework

open access: yes, 2017
We perform clustering of categorical data using the Information Bottleneck, (IB), framework at large scale. We examine the performance of existing solutions using multiple machine architectures.
Natasa Tagasovska   +3 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The Compound Information Bottleneck Outlook

open access: yesCoRR, 2022
This work has been submitted to the IEEE for possible ...
Michael Dikshtein   +2 more
openaire   +3 more sources

Shared-Private Information Bottleneck Method for Cross-Modal Clustering

open access: yesIEEE Access, 2019
Recently, the cross-modal analysis has drawn much attention due to the rapid growth and widespread emergence of multimodal data. It integrates multiple modalities to improve learning and generalization performance.
Xiaoqiang Yan   +3 more
doaj   +1 more source

Information Bottleneck as Optimisation Method for SSVEP-Based BCI

open access: yesFrontiers in Human Neuroscience, 2021
In this study, the information bottleneck method is proposed as an optimisation method for steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI).
Anti Ingel, Raul Vicente
doaj   +1 more source

An Alphabet-Size Bound for the Information Bottleneck Function [PDF]

open access: yes, 2020
The information bottleneck function gives a measure of optimal preservation of correlation between some random variable X and some side information Y while compressing X into a new random variable W with bounded remaining correlation to X.
Christoph Hirche   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Hierarchical clustering based on the information bottleneck method using a control process

open access: yes, 2015
Clustering techniques aim organizing data into groups whose members are similar. A key element of these techniques is the definition of a similarity measure.
Sbert, M.   +4 more
core   +1 more source

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