Results 71 to 80 of about 15,576,316 (273)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
EURASIP Journal on Audio, Speech, and Music ProcessingMulti-head attention mechanisms have been widely applied in speech pre-training. However, their roles and effectiveness in various downstream tasks have not been fully explored. Attention heads may vary in importance depending on the downstream task.
Yukun Qian, Xuyi Zhuang, Mingjiang Wang
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Sequential Invariant Information Bottleneck
ICASSP 2023 - 2023 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2023 Previous approaches to the problem of generalization for out-of-distribution (OOD) data usually assume that data from each environment is available simultaneously, which is unrealistic in real-world applications. In this paper, we develop a new framework termed the sequential invariant information bottleneck (seq-IIB) to improve the generalization ...
Zhang, Yichen, Yu, Shujian, Chen, Badong
openaire +3 more sources
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Information Bottleneck on General Alphabets [PDF]
2018 IEEE International Symposium on Information Theory (ISIT), 2018 We prove rigorously a source coding theorem that can probably be considered folklore, a generalization to arbitrary alphabets of a problem motivated by the Information Bottleneck method. For general random variables $(Y, X)$, we show essentially that for some $n \in \mathbb{N}$, a function $f$ with rate limit $\log|f| \le nR$ and $I(Y^n; f(X^n)) \ge nS$
Georg Pichler, Günther Koliander
openaire +4 more sources
Independent Component Analysis Based on Information Bottleneck
Abstract and Applied Analysis, 2015 The paper is mainly used to provide the equivalence of two algorithms of independent component analysis (ICA) based on the information bottleneck (IB). In the viewpoint of information theory, we attempt to explain the two classical algorithms of ICA by ...
Qiao Ke +4 more
doaj +1 more source
Gaussian information bottleneck and the non-perturbative renormalization group
New Journal of Physics, 2022 The renormalization group (RG) is a class of theoretical techniques used to explain the collective physics of interacting, many-body systems. It has been suggested that the RG formalism may be useful in finding and interpreting emergent low-dimensional ...
Adam G Kline, Stephanie E Palmer
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PHONON BOTTLENECK IN PARAMAGNETIC CRYSTALS [PDF]
, 1965 A unified treatment of phonon bottleneck theory is given, using a thermodynamic method which includes both the direct and Orbach processes. The key parameter is the phonon relaxation time, which is calculated in a variety of cases, including several in ...
STONEHAM, AM
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source