Results 151 to 160 of about 2,875,027 (345)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Accidental Exposure to Poisonous Houseplants: An Analysis of Cases Reported to Poison Information Centers. [PDF]

Dtsch Arztebl Int
Pietsch J, Acquarone D, Holzer A, Arif T, Fuchs J, Deters M, Begemann K, Hermanns-Clausen M.   +7 more
europepmc   +1 more source

SOD1 gene screening in ALS – frequency of mutations, patients’ attitudes to genetic information and transition to tofersen treatment in a multi-center program

Thomas Meyer, Peggy Schumann, Torsten Grehl, Ute Weyen, Susanne Petri, Annekathrin Rödiger, Robert Steinbach, Julian Großkreutz, Sarah Bernsen, Patrick Weydt, Joachim Wolf, René Günther, Maximilian Vidovic, Petra Baum, Moritz Metelmann, Jochen H. Weishaupt, Berthold Streubel, David C. Kasper, Yasemin Koc, Dagmar Kettemann, Jenny Nordén, Philipp Schmitt, Bertram Walter, Christoph Münch, Susanne Spittel, André Maier, Peter Körtvélyessy   +26 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Intoxications and knowledge about toxicological information centers in undergraduate students in the state of Jalisco, Mexico. [PDF]

Aten Primaria
Rojas-Prado E, Hernández-Pérez MA, Vázquez-Alvarez AO, Huerta-Olvera SG.   +3 more
europepmc   +1 more source

Integration of Security Architecture and Green Information Technology in the Implementation of Nextcloud in a Data Center

Tio Pambudi, Patah Herwanto
openalex   +2 more sources

Non-government information resource centers in the United States: providing information on laboratory and field animal welfare

, 1992
Lee Krulisch
openalex   +2 more sources

Sue Brown, The syntax of negation in Russian: a Minimalist approach (Stanford Monographs in Linguistics). Stanford: Center for the Study of Language and Information, 1999. Pp. xii+154. [PDF]

, 2001
Paul Rowlett
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Newsletter [PDF]

, 1991
International Association of Aquatic and Marine Science Libraries and Information Centers
core   +6 more sources