Results 171 to 180 of about 15,311,848 (309)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The incidence, frequency of late liver-related complications, and transplant likelihood in pediatric acute liver failure in Californian children. [PDF]

Hepatol Commun
Lee JTC, Barbetta A, Ascher Bartlett J, Bangerth S, Jordan S, Lo M, Barhouma S, Houshmand L, Sher L, Kohli R, Etesami K, Emamaullee J.   +11 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

KaSARi: a national framework for standardized, automated, and predictive radiotherapy in Finland. [PDF]

Acta Oncol
Seppälä J, Tengström M, Korkalainen H, Virén T, Honkanen JT, Nikkinen J, Lehtiö K, Ålgars A, Keyriläinen J, Suilamo S, Nurmi H, Skyttä T, Boman E, Vatanen T, Sailas L, Arkko UM, Vuolukka K, Koivumäki T, Metsäharju T, Voivalin T, Heikkilä J.   +20 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A national-wide analysis of dental services utilization in primary health care settings in rural areas of Iran. [PDF]

J Educ Health Promot
Pouraghasi L, Olyaeemanesh A, Nouhi M, Jafari M.   +3 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Recruiting children and young people with vision impairment for clinical research - experience from the SeeMyLife study. [PDF]

BMC Med Res Methodol
Gittel L, Finger RP, Richter V, Cadi A, Beck N, Colombo A, Gelžinis A, Gustafierro E, Incagli F, Kručaitė A, Lanza M, Leonardi M, Leroy BP, Nowakowska D, Nowomiejska K, Parmeggiani F, Pelletier V, Philippe A, Reffo ME, Slaghmuylder Y, Suppiej A, Laeng C, Žemaitienė R, Dollfus H, Terheyden JH, SeeMyLife consortium members.   +25 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The National Cancer Institute's Cancer Information Service: 50 years of service to the nation. [PDF]

J Natl Cancer Inst
Vanderpool RC.
europepmc   +1 more source