Results 51 to 60 of about 23,833,705 (251)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Information and Communication Technologies in Tourism 2018: Proceedings of the International Conference in Jönköping, Sweden, January 24-26, 2018 [PDF]

open access: yes, 2019
Analyzes the use of information and communication technologies within the travel and tourism sectors Explores the development of digital strategies, including digital marketing, and the impact of big data Presents both the latest research findings and ...

core  

Towards Robust Evaluation of Aesthetic and Photographic Quality Metrics: Insights from a Comprehensive Dataset

open access: yesComplexity
In recent years, the development of metrics to evaluate image aesthetics and photographic quality has proliferated. However, validating these metrics presents challenges due to the inherently subjective nature of aesthetics and photographic quality ...
Iria Santos   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Information and communication technologies and geographic concentration of manufacturing industries: Evidence from China [PDF]

open access: yes
Using the 2004 China economic census database, this paper examines the impact of information and communication technologies (ICT) on the geographic concentration of manufacturing industries, controlling for other determinants of industrial agglomeration.
Fu, Shihe, Hong, Junjie
core   +2 more sources

The mathematical method for assessing the cybersecurity state of cloud services

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
This study presents the developed mathematical method for assessing the cybersecurity state of cloud services of information infrastructure facilities.
Yevheniia Ivanchenko   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Performance evaluation of Cuckoo filters as an enhancement tool for password cracking

open access: yesCybersecurity, 2023
Cyberthreats continue their expansion, becoming more and more complex and varied. However, credentials and passwords are still a critical point in security.
Maria-Dolores Cano   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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