Results 131 to 140 of about 8,703,712 (260)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Semantic Similarity of Words in a Taxonomy: A Fuzzy and Multiple-Context Approach

IEEE Access
In this paper, the semantic similarity of words organized according to a taxonomy is investigated. For this purpose, word senses are fundamental, and word senses depend on contexts.
Anna Formica, Ida Mele, Francesco Taglino   +2 more
doaj   +1 more source

MICFuzzy: A maximal information content based fuzzy approach for reconstructing genetic networks. [PDF]

PLoS One, 2023
Nakulugamuwa Gamage H, Chetty M, Lim S, Hallinan J.   +3 more
europepmc   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Entropy of Volatility Changes: Novel Method for Assessment of Regularity in Volatility Time Series

Entropy
The goal of this research is to introduce and thoroughly investigate a new methodology for the assessment of sequential regularity in volatility time series. Three volatility estimators based on daily range data are analyzed: (1) the Parkinson estimator,
Joanna Olbryś
doaj   +1 more source

spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content. [PDF]

Nat Commun, 2023
De Jonghe J, Kaminski TS, Morse DB, Tabaka M, Ellermann AL, Kohler TN, Amadei G, Handford CE, Findlay GM, Zernicka-Goetz M, Teichmann SA, Hollfelder F.   +11 more
europepmc   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Information content. [PDF]

Circulation, 1981
openaire   +2 more sources

Information content of exchange rate volatility: Turkish experience [PDF]

This study constructs an empirical model of the volatility of the TL/US$ exchange rate for the Turkish economy during the post-2001 crisis period ending on August 2006.
Levent, Korap
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source