Results 161 to 170 of about 3,194,155 (315)

Playing games with information: investigating perceptions of a mobile content sharing game

, 2012
We introduce Indagator (Latin for explorer), an application which incorporates multiplayer, pervasive gaming elements into mobile content sharing. Indagator allows users to annotate real world locations with multimedia content, and concurrently, provides
Chua, Alton Yeow Kuan, Lee, Chei Sian, Goh, Dion Hoe-Lian   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Design of Object-based Information System Prototype

, 2014
Researchers who use science and technology information were found to ask an information service in which they can excerpt the contents they needed, rather than using the information at article level. In this study, we micronized the contents of scholarly
Kim, hyesun, Shin, Sumi, Yoo, Suhyeon
core  

Creating Library Website Using Open Source Content Management System [PDF]

, 2007
Library website is considered as communication tool, which help to create and publish the information regarding its activities and services. Creation and maintenance of an interactive library website consumes technical expertise, money and time.
Vimal Kumar, V.
core  

Surpresas na política monetária e a estrutura a termo da taxa de juros brasileira

Economia Aplicada, 2004
This paper empirically assesses the monetary policy's surprise effect over the interest rate curve, testing the impacts of COPOM's (monetary policy Committee) decisions over the interest rates curve (Swaps rates with maturity to 1, 2, 3, 6 and 12 months)
Benjamin Miranda Tabak, Alícia Tabata
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Generalizing the information content for stepped wedge designs: A marginal modeling approach. [PDF]

Scand Stat Theory Appl, 2023
Li F, Kasza J, Turner EL, Rathouz PJ, Forbes AB, Preisser JS.   +5 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimizing Microsatellite Marker Panels for Genetic Diversity and Population Genetic Studies: An Ant Colony Algorithm Approach with Polymorphic Information Content. [PDF]

Biology (Basel), 2023
Rasoarahona R, Wattanadilokchatkun P, Panthum T, Thong T, Singchat W, Ahmad SF, Chaiyes A, Han K, Kraichak E, Muangmai N, Koga A, Duengkae P, Antunes A, Srikulnath K.   +13 more
europepmc   +1 more source