Results 31 to 40 of about 1,481,445 (269)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

L’Observatoire de l’infox : un dispositif éducatif pour développer une culture citoyenne de l’information au Brésil

open access: yesRevue Internationale d’Éducation de Sèvres
Inspired by Paulo Freire’s pedagogy of autonomy, this text advocates for an educational paradigm that fosters critical awareness, curiosity, and ethical discernment in the context of online information.
Lorena Tavares de Paula
doaj   +1 more source

ABOUT THE QUESTION OF THE PERIODIZATION OF HISTORY IN THE PARADIGM OF THE INFORMATION APPROACH

open access: yesRUDN Journal of World History, 2018
The information approach allows us to distinguish two principal stages in the history of mankind, the stage of oral culture, covering the entire non-written period of history, and the stage of written culture.
Alikber Kalabekovich Alikberov
doaj   +1 more source

Information Politics and Information Culture: A Case Study [PDF]

open access: yesInforming Science: The International Journal of an Emerging Transdiscipline, 2005
This article introduces the concepts of information politics and information culture and presents a case study that explores these concepts. The literature from the areas of IS theory and organization theory that provides a backdrop to these concepts is discussed.
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The embeddedness of collaborative information seeking in information culture

open access: yesJournal of Information Science, 2016
Professionally, people often conduct their work in settings containing a range of different collaborative situations and work practices in which people handle information and work activities. Still, work tasks are usually considered and perceived as individual activities although the technology and the characteristics of the tasks require ...
Preben Hansen, Gunilla Widén
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

THE IMPACT OF INFORMATION AND COMMUNICATION TECHNOLOGIES (ICT) ON THE DIGITAL TRANSFORMATION OF SOCIETY: A SOCIO-PHILOSOPHICAL ANALYSIS

open access: yesОсвітній дискурс
Urgency of the research. Information and communication technologies (ICTs) play a fundamental role in the digital transformation of society, changing the way we do business, communicate and govern.
Andrii Krupa, Victoriya Marienko
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy