Results 31 to 40 of about 1,481,445 (269)
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Inspired by Paulo Freire’s pedagogy of autonomy, this text advocates for an educational paradigm that fosters critical awareness, curiosity, and ethical discernment in the context of online information.
Lorena Tavares de Paula
doaj +1 more source
ABOUT THE QUESTION OF THE PERIODIZATION OF HISTORY IN THE PARADIGM OF THE INFORMATION APPROACH
The information approach allows us to distinguish two principal stages in the history of mankind, the stage of oral culture, covering the entire non-written period of history, and the stage of written culture.
Alikber Kalabekovich Alikberov
doaj +1 more source
Information Politics and Information Culture: A Case Study [PDF]
This article introduces the concepts of information politics and information culture and presents a case study that explores these concepts. The literature from the areas of IS theory and organization theory that provides a backdrop to these concepts is discussed.
openaire +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The embeddedness of collaborative information seeking in information culture
Professionally, people often conduct their work in settings containing a range of different collaborative situations and work practices in which people handle information and work activities. Still, work tasks are usually considered and perceived as individual activities although the technology and the characteristics of the tasks require ...
Preben Hansen, Gunilla Widén
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Urgency of the research. Information and communication technologies (ICTs) play a fundamental role in the digital transformation of society, changing the way we do business, communicate and govern.
Andrii Krupa, Victoriya Marienko
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

