Results 71 to 80 of about 1,481,445 (269)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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RECIIS, 2009 To complete communication between researchers studies and science popularization studies a new way in scientific communication is open by the author, the one between professionals and researchers.
Viviane Couzinet
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DEVELOPMENT OF INFORMATION CULTURE OF STUDENTS OF HUMANITARIAN SPECIALITIES
Інформаційні технології і засоби навчання, 2019 Issues related to information culture evoke a natural interest of Ukrainian and foreign researchers. In addition to purely technical aspects and the development of competency characteristics, the problem of the development of students’ information ...
Анатолій Володимирович Вихрущ +5 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Cultures in Information Systems Development
, 2019 Modelling is an essential part of information systems development. Models are used for communication between interest groups and inside development teams. Models are also used for transferring baseline artefacts between development phases. Models are mainly developed by humans, which represent certain cultures - national, enterprise, professional, team,
Hannu Jaakkola, Bernhard Thalheim
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 This article examines the approaches to the definition of “information culture”, its components, the system of personal values needed to succeed in the information and professional activities, the problem of students’ information culture formation in the
Светлана Николаевна Лапина
doaj
Law and culture in the information society [PDF]
The Information Society, 1986 Abstract The paper attempts to reconcile the conflicting concerns about information as a public resource and information as an economic commodity within an information society. The free and uncompensated distribution of information can be rationalized within the context of an agricultural or manufacturing society as a means for furthering the economic ...
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source