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Public Health Information Dissemination [PDF]
Our Mission: To strengthen public health science and improve public health decision making and practice to achieve positive health outcomes.Our Services: Clinicians, public health professionals, policymakers, communities, and individuals need timely ...
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Systematic Review of Tools and Approaches for Evaluating the Transferability of Health Technology Assessments Across Different Jurisdictions [PDF]
International Journal of Health Policy and ManagementBackground This study aims to review tools that have been developed for the transferability of health technology assessment (HTA) information to different countries.
Elham Ahmadnezhad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Persistent Localized Broadcasting in VANETs [PDF]
, 2013 We present a communication protocol, called LINGER, for persistent dissemination of delay-tolerant information to vehicular users, within a geographical area of interest.
Borsetti, Diego Ferruccio +7 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Survey on Transmission Optimization Technologies for Federated Large Language Model Training [PDF]
Jisuanji kexueWith the rapid development of artificial intelligence technology,various types of large language models are emerging.However,most users and datasets participating in dedicated large language models have certain requirements for privacy and security,the ...
DUN Jingbo, LI Zhuo
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
, 2012 This chapter outlines key issues of evidence-based theories and frameworks for policy dissemination research, discusses policy intervention design, and specifies potential challenges that may be faced in policy dissemination research.
Elizabeth A. Dodson +5 more
core +1 more source