Results 91 to 100 of about 223,434 (309)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Information Entropy and Its Application for Information Security Tasks

open access: yesБезопасность информационных технологий, 2014
The article deals with information entropy application in information security and its efficiency. The article provides an analysis of entropy properties and dependences and their impact on results of solving modern information security tasks.
Vesta Sergeevna Matveeva
doaj  

Contrast Information Dynamics: A Novel Information Measure for Cognitive Modelling [PDF]

open access: yes
We present contrast information, a novel application of some specific cases of relative entropy, designed to be useful for the cognitive modelling of the sequential perception of continuous signals.
Homer, ST   +5 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Entropy and the value of information for investors [PDF]

open access: yes
Consider any investor who fears ruin facing any set of investments that satisfy no-arbitrage. Before investing, he can purchase information about the state of nature in the form of an information structure. Given his prior, information structure alpha is
Roberto Serrano   +2 more
core   +2 more sources

Role of mutual information in entropy production under information exchanges

open access: yesNew Journal of Physics, 2013
We relate the information exchange between two stochastic systems to the nonequilibrium entropy production in the whole system. By deriving a general formula that decomposes the total entropy production into the thermodynamic and informational parts, we ...
Takahiro Sagawa, Masahito Ueda
doaj   +1 more source

Clinical Value of Information Entropy Compared with Deep Learning for Ultrasound Grading of Hepatic Steatosis

open access: yes, 2020
Entropy is a quantitative measure of signal uncertainty and has been widely applied to ultrasound tissue characterization. Ultrasound assessment of hepatic steatosis typically involves a backscattered statistical analysis of signals based on information ...
Yu-Wei Tsai   +6 more
core   +1 more source

The Constant Information Radar [PDF]

open access: yes, 2016
: The constant information radar, or CIR, is a tracking radar that modulates target revisit time by maintaining a fixed mutual information measure. For highly dynamic targets that deviate significantly from the path predicted by the tracking motion model,

core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Quantum-inspired information entropy in multifield turbulence

open access: yesPhysical Review Research
An information entropy for turbulence systems with multiple field quantities is formulated, as a new paradigm to explore the nonlinear dynamics and pattern formations.
Go Yatomi, Motoki Nakata
doaj   +1 more source

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