Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
An information fractal dimensional relative entropy
Shannon entropy is used to measure information uncertainty, while the information dimension is used to measure information complexity. Given two probability distributions, the difference can be measured by relative entropy. However, the existing relative
Jingyou Wu
doaj +1 more source
Estimation of Cost Allocation Coefficients at the Farm Level Using an Entropy Approach [PDF]
This paper aims to estimate the farm cost allocation coefficients from whole farm input costs. An entropy approach was developed under a Tobit formulation and was applied to a sample of farms from the 2004 FADN data base for Alentejo region, Southern ...
Rui Fragoso, Maria Leonor Carvalho
core
Measures of effectiveness for data fusion based on information entropy [PDF]
This thesis is concerned with measuring and predicting the performance and effectiveness of a data fusion process. Its central proposition is that information entropy may be used to quantify concisely the effectiveness of the process.
Noonan, C.A., Noonan, Colin Anthony
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Improved method for detecting weak abrupt information based on permutation entropy
As a dynamic detecting method for abrupt information, permutation entropy could effectively reflect the subtle change in time series data, which is also simple and can be computed conveniently.
Yongjun Shen, Junfeng Wang, Shaopu Yang
doaj +1 more source
Assessment of the quality of educational portals
The article describes the results of theoretical and experimental studies on the evaluation of the quality of educational information placed on information and educational portals.
R. G. Bolbakov, V. Y. Tsvetkov
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Relative information entropy in cosmology: The problem of information entanglement
The necessary information to distinguish a local inhomogeneous mass density field from its spatial average on a compact domain of the universe can be measured by relative information entropy.
Viktor G. Czinner, Filipe C. Mena
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

