Results 81 to 90 of about 223,434 (309)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
An information fractal dimensional relative entropy
AIP AdvancesShannon entropy is used to measure information uncertainty, while the information dimension is used to measure information complexity. Given two probability distributions, the difference can be measured by relative entropy. However, the existing relative
Jingyou Wu
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Estimation of Cost Allocation Coefficients at the Farm Level Using an Entropy Approach [PDF]
This paper aims to estimate the farm cost allocation coefficients from whole farm input costs. An entropy approach was developed under a Tobit formulation and was applied to a sample of farms from the 2004 FADN data base for Alentejo region, Southern ...
Rui Fragoso, Maria Leonor Carvalho
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Relative information entropy in cosmology: The problem of information entanglement
Physics Letters B, 2016 The necessary information to distinguish a local inhomogeneous mass density field from its spatial average on a compact domain of the universe can be measured by relative information entropy.
Viktor G. Czinner, Filipe C. Mena
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Free and classical entropy over the circle. [PDF]
, 2007 Relative entropy with respect to normalized arclength measure on the circle is greater than or equal to the negative logarithmic energy (Voiculescu's negative free entropy) and is greater than or equal to the modified relative free entropy.
Blower, Gordon
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Assessment of the quality of educational portals
Открытое образование (Москва), 2017 The article describes the results of theoretical and experimental studies on the evaluation of the quality of educational information placed on information and educational portals.
R. G. Bolbakov, V. Y. Tsvetkov
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Some Upper Bounds for Relative Entropy and Applications
, 1998 In this paper we derive some upper bounds for the relative entropy D(p || q) of two probability distribution and apply them to mutual information and entropy mapping.
Sunde, J +2 more
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