Results 51 to 60 of about 22,562,587 (292)
Information environment and information environment of science: essence and purpose
, 2015 Importance. For any discipline, it is important to have a clear conceptual apparatus. Of particular importance are interdisciplinary terms, such as «information», «environment», «space» and their derivatives. In studies of the process of informatization, as well as thematic legal documents, the terms «information environment», «information space» are ...
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mediatization of politics and political manipulation as components of information warfare
Современная наука и инновацииThe article examines the penetration of the media component into information warfare, which leads to significant transformations in the logic and functional interface of decision-making at the political level, as well as to changes in the internal ...
M. S. Pogosova
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Evaluation of the JISC Information Environment: student perceptions
Information Research: An International Electronic Journal, 2003 The Joint Information Systems Committee (JISC) Information Environment (IE, a development from the DNER - Distributed National Electronic Resource, is intended to help users in the UK academic sector maximise the value of published information resources ...
Jillian R. Griffiths
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Exploring the Relationship Between Corporate Social Responsibility and Organizational Resilience
SystemsThis study constructs a conceptual model based on the relationship between corporate social responsibility (CSR) and organizational resilience based on stakeholder theory, resource dependence theory, information asymmetry theory, and signaling theory ...
Rongbin Ruan, Zuping Zhu
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The State of the Kansas Environment, 2010
, 2010 No known reports between 2003 and 2007 2008 onward published biennially The publication of the 2008 Kansas Environment report represents the return to a biennial report for the Division of Environment at the Kansas Department of Health and Environment." -
Kansas. Department of Health and Environment
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source