Results 71 to 80 of about 22,562,587 (292)

Modelling Context for Information Environments [PDF]

open access: yes, 2004
Context-awareness has become an important consideration in the development of mobile and ubiquitous systems. While efforts have been made to develop general context models and application frameworks, it remains the case that often the notion of context supported is very restrictive and/or the representation of context is based on simple key-value pairs.
Belotti, Rudi   +4 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Understanding and Pursuing Information Advantage

open access: yesThe Cyber Defense Review, 2020
The information environment (IE) and operations in and through the IE are currently a particular point of emphasis within the Department of Defense (DoD).
Christopher Paul
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Environmental radiation surveillance in Kansas: July, 1983 thru June, 1984

open access: yes, 1984
"Fall, 1984." "The Environmental Radiation.Surveillance Program is one of several radiological health programs in the Radiation Control Program of the Bureau of Air Quality and Radiation Control, Division of Environment, Kansas Department ...
Kansas Division of Environment.
core   +1 more source

Language as information system: transfer and saving of the information

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The paper is devoted to research of the language system as an information system. The language is not the information itself. It contains information minimum and has information restrictions.
Irina Mikhaylovna Nekipelova
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Fake News Exposure and Financial Performance in Professional Football: A Panel Analysis of Listed European Clubs [PDF]

open access: yesAmfiteatru Economic
The study examined whether the information environment influences the financial performance of publicly listed European football clubs by incorporating variables associated with disinformation into the analysis of football business.
Marius Alin Baciu   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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