Results 111 to 120 of about 1,980,992 (307)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The Influence of System User Ethics in Increasing the Effectiveness of Accounting Information Systems

open access: diamond, 2021
Elly Halimatusadiah   +4 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Information Ethics

open access: yes
This entry provides a comprehensive description of information ethics, a concept applied to numerous domains, especially to ICT, library and information science, social epistemology, media and journalism. The first part of the entry provides a definition of information ethics by some key authors in the field and summarizes the history of this concept ...
openaire   +1 more source

Ethically Informed Design

open access: yesInternational Journal of Designs for Learning
This design case presents my experiences, successes, and challenges, in the design and delivery of a six-week special topics course on culturally inclusive instructional design. The course was delivered synchronously with a diverse group of 15 individuals enrolled in the instructional design and technology degree program.
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

On ethics and information

open access: yesIndian Journal of Plastic Surgery, 2007
Thatte Mukund
doaj   +3 more sources

Code of Ethics of the Association of Austrian Librarians (English version)

open access: yesMitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare
Information Ethics Working Group Association of Austrian Librarians
doaj   +1 more source

Home - About - Disclaimer - Privacy