Results 191 to 200 of about 6,011,536 (233)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Evaluating Information Assurance Strategies*
Decision Support Systems, 2005The information revolution has provided new and improved capabilities to rapidly disseminate and employ information in decision-making. Enhancing and enabling for today's modern industry, these capabilities are critical to our national infrastructures.
J.Todd Hamill +2 more
openaire +1 more source
Evaluating Clinical Information Systems
JONA: The Journal of Nursing Administration, 2003As members of organizational committees to evaluate and select clinical information systems, nurse executives must identify a system that not only has the core functionality to support necessary changes in workflow and optimize nurse productivity and patient safety but that also is embraced by the nursing staff.
Debra, Kirkley, Demi, Rewick
openaire +2 more sources
2014
Evaluation in the context of information services has mainly looked at three distinct areas: service performance evaluation, information retrieval evaluation, and information flow evaluation. This last area, especially used in archives and designated as “appraisal,” aims to define the information’s fate after several years of use, and its purpose is to
Armando Malheiro da Silva +1 more
openaire +1 more source
Evaluation in the context of information services has mainly looked at three distinct areas: service performance evaluation, information retrieval evaluation, and information flow evaluation. This last area, especially used in archives and designated as “appraisal,” aims to define the information’s fate after several years of use, and its purpose is to
Armando Malheiro da Silva +1 more
openaire +1 more source
Evaluation Review, 1990
Evaluation by members of the formal care system of clients' informal supports must overcome conceptual, methodological, and ethical dilemmas if it is to be reliable and valid. Several of these dilemmas are illustrated in a study of elderly social service clients in Jerusalem. The findings point to the need for measurement efforts (1) to focus upon the
Howard Litwin, Gail K. Auslander
openaire +1 more source
Evaluation by members of the formal care system of clients' informal supports must overcome conceptual, methodological, and ethical dilemmas if it is to be reliable and valid. Several of these dilemmas are illustrated in a study of elderly social service clients in Jerusalem. The findings point to the need for measurement efforts (1) to focus upon the
Howard Litwin, Gail K. Auslander
openaire +1 more source
Evaluating Medical Information
1986Modern doctors have access to a large variety of clinical data. These data, whether gathered from patient histories, physical examinations, or laboratory tests, are rarely able to discriminate perfectly between truly symptomatic and “normal” patients.
Steven Schwartz, Timothy Griffin
openaire +1 more source
Information Warfare: Evaluating Information Targets.
1996Abstract : Information Warfare in its broadest definition has existed since armed conflict began. As the pace of battle accelerates and information collection intensifies it is necessary to have a means of synergistically combining the advanced technological tools, organizational structure and mathematical analysis of information target vulnerabilities.
openaire +1 more source
Information Systems Evaluation
2013Due to the prevalent use of Information Systems (IS) in modern organisations, evaluation research in this field is becoming more and more important. In light of this, a set of rigorous methodologies were developed and used by IS researchers and practitioners to evaluate the increasingly complex IS implementation used.
Si Chen +2 more
openaire +1 more source