Results 91 to 100 of about 3,082,391 (312)

Information Extraction Under Privacy Constraints

open access: yes, 2016
A privacy-constrained information extraction problem is considered where for a pair of correlated discrete random variables $(X,Y)$ governed by a given joint distribution, an agent observes $Y$ and wants to convey to a potentially public user as much ...
Alajaji, Fady   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Automatic supervised information extraction of structured web data [PDF]

open access: yes, 2019
The overall purpose of this project is, in short words, to create a system able to extract vital information from product web pages just like a human would. Information like the name of the product, its description, price tag, company that produces it,
Pérez Ruiz, David
core  

Entity Extraction of Key Elements in 110 Police Reports Based on Large Language Models

open access: yesApplied Sciences
With the rapid advancement of Internet technology and the increasing volume of police reports, relying solely on extensive human labor and traditional natural language processing methods for key element extraction has become impractical.
Xintao Xing, Peng Chen
doaj   +1 more source

Enhanced Neural Beamformer with Spatial Information for Target Speech Extraction [PDF]

open access: green, 2023
Aoqi Guo   +6 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

GEOSatDB: global civil earth observation satellite semantic database

open access: yesBig Earth Data
Satellite remote sensing, characterized by extensive coverage, frequent revisits, and continuous monitoring, provides essential data support for addressing global challenges.
Ming Lin, Meng Jin, Juanzi Li, Yuqi Bai
doaj   +1 more source

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