Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
SynthNID: Synthetic Data to Improve End-to-end Bangla Document Key Information Extraction [PDF]
, 2023 Syed Mostofa Monsur +2 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Unstructured Document Information Extraction Method with Multi-Faceted Domain Knowledge Graph Assistance for M2M Customs Risk Prevention and Screening Application [PDF]
Fengchun Tian +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Mention-Agnostic Information Extraction for Ontological Annotation of Biomedical Articles [PDF]
Oumaima El Khettari +7 more
openalex +1 more source
The threshold determination methods of water body information extraction using GF-1 satellite image [PDF]
, 2019 Ruipeng Ji +4 more
openalex +1 more source
Semi-automated extraction of information on open datasets mentioned in articles v2 [PDF]
, 2023 Anastasiia Iarkaeva +4 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
DISCIE–Discriminative Closed Information Extraction [PDF]
Cedric Möller, Ricardo Usbeck
openalex +1 more source