Results 161 to 170 of about 3,126,299 (284)

A review for navigating the trade-offs: evaluating open-source and proprietary large language models for clinical and biomedical information extraction. [PDF]

Front Digit Health
Sugihara Y, Milosavljevic A, Jankovskaja S, Falk M.   +3 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Human level information extraction from clinical reports with finetuned language models. [PDF]

Sci Rep
Liu L, Lian L, Hao Y, Pace A, Kim E, Homsi N, Pershad Y, Lai L, Gracie T, Kishtagari A, Carroll PR, Bick AG, Odisho AY, Chung M, Yala A.   +14 more
europepmc   +1 more source

Unsupervised Information Extraction with Distributional Prior Knowledge [PDF]

, 2011
CHAI, Kian Ming A., Chieu, Hai Leong, JIANG, Jing, LEUNG, Cane Wing-ki, Teow, Loo-Nin   +4 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Neuro-symbolic AI for auditable cognitive information extraction from medical reports. [PDF]

Commun Med (Lond)
Prenosil GA, Weitzel TK, Bello SC, Mingels C, Manzini G, Meier LP, Shi KY, Rominger A, Afshar-Oromieh A.   +8 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

ZebraMap: A Multimodal Rare Disease Knowledge Map with Automated Data Aggregation & LLM-Enriched Information Extraction Pipeline. [PDF]

Diagnostics (Basel)
Islam MS, Jamal A, Alkhathlan A.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Leveraging large language models for structured information extraction from pathology reports. [PDF]

J Pathol Inform
Balasubramanian JB, Adams D, Roxanis I, de Gonzalez AB, Coulson P, Almeida JS, García-Closas M.   +6 more
europepmc   +1 more source