Results 231 to 240 of about 3,082,391 (312)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

On the use of Silver Standard Data for Zero-shot Classification Tasks in Information Extraction [PDF]

Jianwei Wang, Tian‐Yin Wang, Ziqian Zeng   +2 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Clinical Information Extraction From Notes of Veterans With Lymphoid Malignancies: Natural Language Processing Study.

JMIR Med Inform
He L, Moldenhauer MR, Zheng K, Ma H.
europepmc   +1 more source

Microllm: a structured information extraction tool using large language models and named entity recognition in microbiology. [PDF]

Brief Bioinform
Lu J, Li F, Feng L, Yu Z, Lu J, Qin M, She S, Jiang H, Guo Z, Xia J, Han L.   +10 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

JAR2ONTOLOGY - A TOOL FOR AUTOMATIC EXTRACTION OF SEMANTIC INFORMATION FROM JAVA OBJECT CODE

, 2011
Nicolás Marı́n, Clara Sáez-Árcija, M.A. Vila   +2 more
openalex   +1 more source

Clinical entity augmented retrieval for clinical information extraction. [PDF]

NPJ Digit Med
Lopez I, Swaminathan A, Vedula K, Narayanan S, Nateghi Haredasht F, Ma SP, Liang AS, Tate S, Maddali M, Gallo RJ, Shah NH, Chen JH.   +11 more
europepmc   +1 more source

Information Extraction [PDF]

, 2011
openaire   +1 more source