Results 71 to 80 of about 3,082,391 (312)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Graphene: A Context-Preserving Open Information Extraction System [PDF]

open access: yes, 2018
We introduce Graphene, an Open IE system whose goal is to generate accurate, meaningful and complete propositions that may facilitate a variety of downstream semantic applications. For this purpose, we transform syntactically complex input sentences into
Cetto, Matthias   +3 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Using Large Language Models for Extracting Structured Information From Scientific Texts

open access: yesCurrent Directions in Biomedical Engineering
Extracting structured information from scientific works is challenging as sought parameters or properties are often scattered across lengthy texts. We introduce a novel iterative approach using Large Language Models (LLMs) to automate this process.
Rettenberger Luca   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Bayesian Information Extraction Network

open access: yes, 2003
Dynamic Bayesian networks (DBNs) offer an elegant way to integrate various aspects of language in one model. Many existing algorithms developed for learning and inference in DBNs are applicable to probabilistic language modeling.
Peshkin, Leonid, Pfeffer, Avi
core   +5 more sources

Bootstrapping Knowledge Graphs From Images and Text

open access: yesFrontiers in Neurorobotics, 2019
The problem of generating structured Knowledge Graphs (KGs) is difficult and open but relevant to a range of tasks related to decision making and information augmentation.
Jiayuan Mao   +7 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Information Extraction and Spatial Distribution of Research Hot Regions on Rocky Desertification in China

open access: yesApplied Sciences, 2018
Rocky desertification is an important type of ecological degradation in southwest of China. The author uses the web crawler technology and obtained 9345 journal papers related to rocky desertification from 1950s to 2016 in China.
Yunfeng Hu, Yueqi Han, Yunzhi Zhang
doaj   +1 more source

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