Results 151 to 160 of about 3,404,905 (311)

Television Journalist as an Agent of Changes: Influence of Media on Social and Political Transformations in Modern Society

open access: yesВісник Київського національного університету культури і мистецтв. Серія: Аудіовізуальне мистецтво і виробництво
The purpose of this research is to analyse the role of a television journalist as an active agent of changes in the processes of social and political transformations; to study how media activity shapes public opinion and initiates social processes; to ...
Володимир Данилюк   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The influence of organizational culture on the outcome of an IS implementation

open access: yes, 2014
A number of information system (IS) studies have adopted organizational culture (OC) theory to investigate IS implementations. The studies highlight that members will reach consensus or agreement in the use of an IS but also experience inevitable ...
Coombs, C, Ravishankar, MN, Abubakre, M
core  

How does information technology– based service degradation influence consumers’ use of services? An information technology–based service degradation decision theory

open access: yes, 2019
Information technology is crucial for modern services. Service delivery may include a complex mix of information technology and telecommunication providers, global networks and customers’ information technology devices.
Newman, Michael; id_orcid   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Abstract Model Counting: A Novel Approach for Quantification of Information Leaks

open access: yes, 2014
acmid: 2590328 keywords: model checking, quantitative information flow, satisfiability modulo theories, symbolic execution location: Kyoto, Japan numpages: 10acmid: 2590328 keywords: model checking, quantitative information flow, satisfiability modulo ...
Quoc-Sang Phan   +4 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

An institutional perspective on information and communication technologies in governance

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Information and Communication Technologies (ICTs) are becoming increasing relevant in policy making and governance activities. However, the broad effects of
Panagiotopoulos, Panagiotis
core  

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