Results 201 to 210 of about 2,767,167 (263)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Examining the relationship between empathetic leadership and organizational citizenship behavior in the architecture, engineering, and construction industry: the roles of altruistic attitude and caring ethical climate. [PDF]

Front Psychol
Liu C, Sun S, Ma G, Ma Q.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Generative artificial intelligence heuristic cues, trust and continuous intention of CBeC platform and the moderating role of information overload. [PDF]

Sci Rep
Li X, Liu H, Zhou T, Hu C, Ramayah T.
europepmc   +1 more source

Assessing the Quality of Consumer Health Information Within the Realm of Shoulder Injuries on TikTok. [PDF]

Orthop J Sports Med
Jawich B, Alqasmi H, Elnaggar A, Kotob S, Abdalla O, Bitar I, Suhrawardy A, Vaidya R.   +7 more
europepmc   +1 more source

Economic information in clinical decision-making: focus group discussions with Finnish general practitioners and patients. [PDF]

BMJ Open
Ahonen JE, Sipilä R, Kortteisto T, Komulainen J.   +3 more
europepmc   +1 more source

The impact of quality of information on classroom engagement with GenAI tools: integrating TAM and SOR framework. [PDF]

Front Psychol
Li F, Chen J, Shao T, Sun J.
europepmc   +1 more source

Uncovering the hierarchical determinants of continuous usage in online health communities: integrating meta-analysis with FUZZY-DEMATEL-AISM. [PDF]

Sci Rep
Cao Z, Liu R, Li Y, Chen C, Cai J.
europepmc   +1 more source

Predicting the Intention to Use Generative Artificial Intelligence for Health Information: Comparative Survey Study.

J Med Internet Res
Matthes J, Reinhardt A, Hodzic S, Kaňková J, Binder A, Bojic L, Maindal HT, Paraschiv C, Ryom K.   +8 more
europepmc   +1 more source