Results 101 to 110 of about 9,293,540 (311)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Computer-derived management information in a special library [PDF]
, 1982 Not the least of the benefits of automating libraries and information centers is the enhanced ability to monitor processes and services, to collect, structure, analyze, and report critical or useful data hitherto largely unavailable or excessively ...
Kennedy, Robert A.
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Information management, today and tomorrow [PDF]
Current problems and future trends in information management are briefly summarized in relation to scientific and technical information management systems and management of management information (planning, marketing, and operations)
Pryor, H. E.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018 In present conditions, the information and communication technology has developed and become popular rapidly. Increasing competition with globalization has been affecting the economic development of the countries.
Sertaç Arı, Esen Şahin
doaj
INFORMATION VALUE IN WEED MANAGEMENT [PDF]
Use of the economic threshold to improve the efficiency of preemergent-herbicide treatment decisions is limited by a lack of weed information. An economic model for assessing the expected value of weed information needed to implement a threshold decision
Allen, P. Geoffrey +3 more
core +1 more source