Results 111 to 120 of about 9,293,540 (311)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
GECONTEC: Revista Internacional de Gestión del Conocimiento y la Tecnología, 2013 Resumen. El Modelo de Gestión de Información y Conocimiento para la empresa en perfeccionamiento (MOGICEP) utiliza la gestión del conocimiento como enfoque gerencial, se sustenta en el marco regulatorio del país para la organización de la información ...
Sara Artiles Visbal +1 more
doaj +1 more source
Information Management: A Consolidation of Operations, Analysis and Strategy [PDF]
, 2002 The book provides an exposition on the discipline of information management. It is organised into four parts. The first of these deals with factors that shape the meaning of information management - the professional associations that have formed; the ...
Middleton, Michael
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Impliance: A Next Generation Information Management Appliance
, 2006 ably successful in building a large market and adapting to the changes of the last three decades, its impact on the broader market of information management is surprisingly limited.
Bhattacharjee, Bishwaranjan +11 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Intellectual Solutions for Development of Information Technologies [PDF]
, 2017 With the development of computer technologies, the meaning invested in the notion of an information system changed. A modern information system is a set of information technologies aimed at supporting the life cycle of information and includes three ...
Komarova, O. I. +2 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Management information systems as an effective instrument for the development of business structures
Путеводитель предпринимателя, 2020 The article presents a modern approach to the formation of an effective tool for the development of business structures based on management information systems.
A. V. Podsevatkin
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