Results 131 to 140 of about 23,986,483 (363)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Performance of Network and Service Monitoring Frameworks [PDF]

11th IFIP/IEEE International Symposium on Integrated Network Management (2009), 2009
The efficiency and the performance of anagement systems is becoming a hot research topic within the networks and services management community. This concern is due to the new challenges of large scale managed systems, where the management plane is integrated within the functional plane and where management activities have to carry accurate and up-to ...
arxiv  

Digital transformation of everyday life – How COVID-19 pandemic transformed the basic education of the young generation and why information management research should care?

International Journal of Information Management, 2020
N. Iivari, Sumita Sharma, Leena Ventä-Olkkonen   +2 more
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Medical Information Management System (MIMS): An automated hospital information system [PDF]

, 1973
Flexible system of computer programs allows manipulation and retrieval of data related to patient care.
Alterescu, S., Collins, L. S., Schwarz, R. A.   +2 more
core   +1 more source

A bull's eye view of management and engineering information systems [PDF]

, 1964
Anthony G. Oettinger
openalex   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, Volume 15, Issue 6, Page 994-1008, June 2025.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

The MAGIC of Data Management: Understanding the Value and Activities of Data Management [PDF]

arXiv
In an era dominated by information technology, the critical discipline of data management remains undervalued compared to the innovations it enables, such as artificial intelligence and social media. The ambiguity surrounding what constitutes data management and its associated activities complicates efforts to explain its importance and ensure data are
arxiv  

Designing Information Revelation and Intervention with an Application to Flow Control [PDF]

arXiv, 2012
There are many familiar situations in which a manager seeks to design a system in which users share a resource, but outcomes depend on the information held and actions taken by users. If communication is possible, the manager can ask users to report their private information and then, using this information, instruct them on what actions they should ...
arxiv  

A file management system for a large corporate information system data bank [PDF]

, 1968
Honien Liu
openalex   +1 more source