Results 71 to 80 of about 185,040 (306)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

CONCEPTUALIZATION OF FINANCIAL DIAGNOSTICS IN THE SYSTEM OF ENTERPRISE'S FINANCIAL AND ECONOMIC SECURITY MANAGEMENT

, 2019
The effectiveness of the financial and economic security management system of enterprise is determined by the information support system which can provide communications and meet user requests at all stages of the management process.
N. Kashchena, Т. Staverska
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Geospatial (s)tools : integration of advanced epidemiological sampling and novel diagnostics [PDF]

, 2013
Large-scale control and progressive elimination of a wide variety of parasitic diseases is moving to the fore. Indeed, there is good pace and broad political commitment.
Giuseppe Cringoli, Rinaldi, L., Robert Bergquist, Cringoli, G., Utzinger, Jürg, Giuseppe Cringoli, Utzinger, J., Bergquist, Robert, Marco Albonico, Rinaldi, Laura, Albonico, M., Albonico, Marco, Laura Rinaldi, Jürg Utzinger, Bergquist, R., Cringoli, Giuseppe   +15 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A non-linear weighted least squares gas turbine diagnostic approach and multi-fuel performance simulation [PDF]

, 2011
The gas turbine which has found numerous applications in Air, Land and Sea applications, as a propulsion system, electricity generator and prime mover, is subject to deterioration of its individual components.
Kamunge, Daniel
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Current project of management guidelines of the patients with nosocomial pneumonia in adults

Бюллетень сибирской медицины, 2017
The nosocomial pneumonia is one of the most (or just “is a”) common hospital infections complicating the disease course and resulting in a fatal outcome. In 2016 the revised version of “Russian national recommendations for Nosocomial pneumonia in adults”
Maria A. Karnaushkina, Andrey G. Maliavin, Leonid I. Dvoretckiy, Sergey V. Yakovlev, Sergey L. Babak, Sergey V. Fedosenko, Margarita P. Suvorova, Natalia F. Razgulyeva, Albina B. Arutyunova   +8 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source