Results 111 to 120 of about 32,097,317 (261)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Design of engineering objects using the information model

open access: yesTrudy Odesskogo Politehničeskogo Universiteta, 2019
Information design of engineering objects is based on using the information models of objects. The information model allows you to create an algorithm for designing and manufacturing the desired object.
Володимир Михайлович Тігарєв   +3 more
doaj  

Sub-series 2: Publications

open access: yes, 2015
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Analysising the technological parameters of the high-temperature thermomechanical treatment of metallic products

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки
Background. The implementation of new technologies in the manufacturing processes of structural steel products allows for the improvement of their operational properties.
V.B. Dement'ev   +2 more
doaj   +1 more source

Method of integrated consideration of factors for calculation of anchor system of pontoons

open access: yesMagazine of Civil Engineering
The work is devoted to the study and analysis of hydrodynamic and climatic loads on hydraulic structures of the Neva Bay – the eastern part of the Gulf of Finland, which is exposed to significant anthropogenic and natural impacts.
Kozinetc Galina   +3 more
doaj   +1 more source

Sub-series 2: Publications

open access: yes, 2017
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy