Results 71 to 80 of about 2,698,561 (300)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Multi-dimensional biochemical information processing of dynamical patterns

, 2018
Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal.
Hasegawa, Yoshihiko
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A Far-Field Helicopter Acoustic Detection Method Based on FRESH Adaptive Filtering

Applied Sciences
Helicopter detection plays a vital role in obtaining critical aerial information promptly and ensuring the safety of lives and property. Since a helicopter’s aerodynamic noise primarily consists of main rotor noise, the cyclostationarity of this noise ...
Yingmeng Tao, Chunhua Wei, Tingting Liu
doaj   +1 more source

Handbook of noise ratings [PDF]

, 1975
Handbook announced in Tech Brief is compendium of information describing multifarious noise methods now in use. Reference material gives user better access to definitions, application, and calculation procedures of current noise rating ...
Bennett, R. L., Pearsons, K. S.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Replica symmetric evaluation of the information transfer in a two-layer network in presence of continuous+discrete stimuli

, 2001
In a previous report we have evaluated analytically the mutual information between the firing rates of N independent units and a set of multi-dimensional continuous+discrete stimuli, for a finite population size and in the limit of large noise.
A. Campa, A. Treves, A. Treves, A. Treves, A. Treves, A. Treves, A. Turiel, Alessandro Treves, C. E. Shannon, E. Korutcheva, E. Korutcheva, E. T. Rolls, I. Samengo, J. P. Nadal, J. P. Nadal, K. Kang, N. Skantzos, S. Panzeri, S. Schulz, V. D. Prete, V. D. Prete, Valeria Del Prete, W. Bialek   +22 more
core   +2 more sources

Information Concealment Through Noise Addition

Procedia Computer Science, 2015
AbstractA novel method of concealing information is proposed. Encrypted data is mixed with noise to add the security. The cost of an attack increases linearly with the size of the added noise. Since generating noise is cheap, the size of noise can be as large as possible.
Budi Rahardjo, Kuspriyanto, Intan Muchtadi-Alamsyah, Marisa W. Paryasto   +3 more
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source