Results 291 to 300 of about 11,028,780 (364)

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Personal health data protection and intelligent healthcare applications under generative adversarial network. [PDF]

Sci Rep
Gao X, Mi W, Feng X.
europepmc   +1 more source

MoS2 Channel‐Enhanced High‐Density Charge Trap Flash Memory and Machine Learning‐Assisted Sensing Methodologies for Memory‐Centric Computing Systems

Advanced Science, EarlyView.
Driven by AI computing demands, this study investigates MoS2 channels for 3D NAND Flash to achieve high‐density, low‐power, and reliable nonvolatile memory. MoS2 enables a large memory window and lower operating voltages with low‐k tunneling layer, demonstrating endurance of 10⁴ cycles and retention of 10⁵ s. Comprehensive analyses and machine learning‐
Ki Han Kim, Ju Han Park, Khang June Lee, Ji‐Won Seo, Yeong Kwon Kim, Junhwan Choi, Min‐Jae Seo, Byung Chul Jang   +7 more
wiley   +1 more source

Effects of privacy concerns on older adults' discontinuous usage intention: the chain mediating effect of technology anxiety and the moderating role of perceived price value. [PDF]

Front Public Health
An J, Wan K, Xiang Z, Zhu X, An J, Yang Y.   +5 more
europepmc   +1 more source

Accelerate Mass Transport of Proton and Carbon Sources by Super‐Hygroscopic and Porous Nanosheets for Continuous CO2‐To‐Ethylene Upgrade

Advanced Science, EarlyView.
The conceptual diagram of the Tillandsia and a localized enlargement of its leaves. Abstract Gas‐water/catalyst triple‐phase interface and the microenvironment play critical roles in the reaction kinetics and production rate of electrochemical carbon dioxide reduction reactions (CO2RR), which steer concerted proton‐electron transfer steps.
Silong Dong, Guobin Wen, Xinyu Yang, Xiaowen Zhang, Shuxuan Liu, Haoyang Xiong, Yinyi Liu, Kai Zong, Hao Li, Yifan Li, Yi Cui, Bohua Ren, Xin Wang, Mingliang Jin, Zhongwei Chen   +14 more
wiley   +1 more source

Anomalous Glassy Thermal Conductivity in a Perovskite Bismuthate Induced by Structural Dynamic Instability

Advanced Science, EarlyView.
Unraveling the underlying mechanisms at the origin of ultra‐low thermal conductivity in pristine crystals is of central relevance to designing new functional materials. Single crystals of the candidate functional material BaBiO3 show an anomalous glassy thermal conductivity, which reveals the role of strong anharmonicity and additional scattering ...
Alexandre Henriques, Mariana S. L. Lima, Gøran J. Nilsen, Matthias J. Gutmann, Steffen Wirth, Walber H. Brito, Valentina Martelli   +6 more
wiley   +1 more source

Bio‐Inspired Strategy for Radiation‐Based Thermal Management and Utilization

Advanced Science, EarlyView.
Biological organisms have evolved remarkable strategies to manage and exploit thermal radiation. This review explores bio‐inspired systems that mimic these adaptations—such as radiative cooling, thermal regulation, thermal insulation, water harvesting, infrared camouflage, and infrared detection—and highlights their application in thermal management ...
Hyung Rae Kim, Won Bae Han, Se‐Yeon Heo, Yun Su Go, Suk‐Won Hwang, Young Min Song   +5 more
wiley   +1 more source

Our Theater of Anonymity. [PDF]

Ethics Hum Res
Meeder S, Doerr M.
europepmc   +1 more source

The Role of Artificial Intelligence in Safeguarding Patient Privacy in Healthcare Systems.

J Pharm Bioallied Sci
Jangid P, Meena A, Prerna R, Hashmi ZH, Kumar V, Bhagtani H.   +5 more
europepmc   +1 more source

A Qualitative Study of the Emotional and Decision-Making Experiences of Mothers Whose Daughter Undergoes Assisted Reproductive Technology with Donor Sperm. [PDF]

Int J Womens Health
Wei Q, Yang X, Hong X, He Y, Fan Z, Wang Z.   +5 more
europepmc   +1 more source