Results 291 to 300 of about 1,628,358 (345)

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

open access: yesAdvanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang   +16 more
wiley   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

open access: yesAdvanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu   +12 more
wiley   +1 more source

Polarized Color Filters Using Colloidal Quantum Rod Nanocrystals for Advanced High‐Performance Displays

open access: yesAdvanced Science, EarlyView.
This groundbreaking research has advanced the utilization of quantum rods (QRs) for the emission of linearly polarized light, resulting in exceptional color saturation and enhanced display efficiency. The developed filter demonstrates a polarization degree of up to 0.67 and an impressive ambient contrast ratio (ACR) of 263:1, setting the stage for ...
Jianxin Song   +12 more
wiley   +1 more source

Navigating sexual orientation and gender identity data privacy concerns in United States genetics practices. [PDF]

open access: yesJ Genet Couns
Zayhowski K   +7 more
europepmc   +1 more source

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan   +11 more
wiley   +1 more source

An innovative randomized response model based on a customizable random tool. [PDF]

open access: yesPLoS One
Aboalkhair AM   +5 more
europepmc   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

open access: yesAdvanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao   +11 more
wiley   +1 more source

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