Results 51 to 60 of about 9,826,920 (308)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

An enhanced DPoS consensus mechanism using quadratic voting in Web 3.0 ecosystem [PDF]

Blockchain
Consensus mechanisms are fundamental to maintaining consistency in distributed systems. With the advent of Web 3.0, blockchain has revealed limitations of traditional Delegated Proof of Stake (DPoS) consensus mechanisms.
Tianyu Lei, Qinnan Zhang, Wangjie Qiu, Hongwei Zheng, Shuyi Miao, Wanqing Jie, Jianming Zhu, Jin Dong, Zhiming Zheng   +8 more
doaj   +1 more source

Citizens’ Information Privacy Protection Model in e-Government for Developing Countries [PDF]

پژوهش‌های مدیریت عمومی, 2016
The most important aim of this study is to propose a model for protecting citizens’ information privacy in e-Government for developing countries. This study develops theoretical foundations and models of e-Government in  judicial-legal dimension.
Mohammad Taghi Taghavifard, Mohammad Reza Taghva, Mehdi Faghihi, Mohammad Javad Jamshidi   +3 more
doaj   +1 more source

Identifying the Effect of Data Breach Publicity on Information Security Awareness Using Hierarchical Regression

IEEE Access, 2021
The technological evolution has formed new challenges for organizations to safeguard their information as digital assets. Information Security Awareness (ISA) is the cognitive state where individuals comprehend information security, threats, and the ...
Hui Na Chua, Jia Sheng Teh, Anthony Herbland   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Hypothesis Testing Under Mutual Information Privacy Constraints in the High Privacy Regime [PDF]

IEEE Transactions on Information Forensics and Security, 2017
Hypothesis testing is a statistical inference framework for determining the true distribution among a set of possible distributions for a given data set. Privacy restrictions may require the curator of the data or the respondents themselves to share data
Jiachun Liao, L. Sankar, V. Tan, Flavio du Pin Calmon   +3 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A novel and highly efficient botnet detection algorithm based on network traffic analysis of smart systems

International Journal of Distributed Sensor Networks, 2022
In smart systems, attackers can use botnets to launch different cyber attack activities against the Internet of Things. The traditional methods of detecting botnets commonly used machine learning algorithms, and it is difficult to detect and control ...
Li Duan, Jingxian Zhou, You Wu, Wenyao Xu   +3 more
doaj   +1 more source

Human Autonomy in the Era of Augmented Reality—A Roadmap for Future Work

Information, 2022
Augmented reality (AR) has found application in online games, social media, interior design, and other services since the success of the smartphone game Pokémon Go in 2016.
David Harborth
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source