Results 71 to 80 of about 1,504,715 (296)

Group privacy management strategies and challenges in Facebook : a focus group study among Flemish youth organizations [PDF]

, 2016
A large body of research has studied young people’s privacy practices and needs in Facebook. Less is known about group privacy. In this study 12 focus groups were organized with a total of 78 adolescents and young adults of local Flemish youth ...
De Wolf, Ralf
core   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparing Threshold Selection Methods for Network Anomaly Detection

IEEE Access
The use of unsupervised machine learning models for anomaly detection is a common thing nowadays. While many research papers focus on improving and testing these models, there is a lack of those that deal with threshold selection, which is an important ...
Adrian Komadina, Mislav Martinic, Stjepan Gros, Zeljka Mihajlovic   +3 more
doaj   +1 more source

Differential Privacy versus Quantitative Information Flow [PDF]

, 2010
Differential privacy is a notion of privacy that has become very popular in the database community. Roughly, the idea is that a randomized query mechanism provides sufficient privacy protection if the ratio between the probabilities of two different ...
Alvim, Mário S., Chatzikokolakis, Konstantinos, Degano, Pierpaolo, Palamidessi, Catuscia   +3 more
core   +3 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Information management and patient privacy [PDF]

BMJ, 1994
EDITOR, - Alison Tonk's editorial was a useful summary of some of the key parts of the NHS Management Executive's information management and technology strategy and will assist in further disseminating the objectives of the strategy to the medical profession.1 Ensuring that the clinical professions are aware and involved is important, and we are making
G P, Winyard, R T, Rogers
openaire   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Sharing, privacy and trust issues for photo collections [PDF]

, 2007
Digital libraries are quickly being adopted by the masses. Technological developments now allow community groups, clubs, and even ordinary individuals to create their own, publicly accessible collections.
Adams, Anne, Cunningham, Sally Jo, Masoodian, Masood   +2 more
core   +1 more source